Article

Virtual Liver Needle Biopsy from Reconstructed Three-Dimensional Histopathological Images: Quantification of Sampling Error

2022-06-12

Abstract excerpt

<h4>Introduction</h4> Prevalently considered as the “gold-standard” for diagnosis of hepatic fibrosis and cirrhosis, the clinical liver needle biopsy is known to be subject to inadequate sampling and a high mis-sampling rate. However, quantifying such sampling bias has been difficult as generating a large number of needle biopsies from the same living patient is practically infeasible. We construct a three-dimens...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 07aee6b4-e99b-5037-9b25-7eb31819946c
DOI: 10.1101/2022.06.08.495226

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Virtual Liver Needle Biopsy from Reconstructed Three-Dimensional Histopathological Images: Quantification of Sampling ErrorDOI 10.1101/2022.06.08.495226Read

LiverMap pipeline for 3D imaging of human liver reveals volumetric spatial dysregulation of cirrhotic vasculobiliary architectureSemantic proximity Read

3D spatially-resolved geometrical and functional models of human liver tissue reveal new aspects of NAFLD progressionSemantic proximity Read

An end-to-end platform for digital pathology using hyperspectral autofluorescence microscopy and deep learning based virtual histologySemantic proximity Read

Liver fibrosis assessments using FibroScan, Virtual-Touch tissue quantification, the FIB-4 index, and Mac-2 binding protein glycosylation isomer levels compared with pathological findings of liver resection specimens in patients with hepatitis C infectionSemantic proximity Read

Improving Frozen Kidney Biopsy Interpretation Using DUET-Generated Virtual PAS StainsSemantic proximity Read

ViFIT-assisted Histopathology: From H&E Style Standardization to Virtual Fiber Image TransformationSemantic proximity Read

Diagnostic Performance of Self-Supervised Foundation Models for Intraoperative Quantification of Hepatic Macrovesicular SteatosisSemantic proximity Read

Validation of virtual trichrome stains for kidney fibrosis evaluation using dual-mode emission and transmission microscopySemantic proximity Read

An end-to-end workflow for non-destructive 3D pathologySemantic proximity Read

Quantitative 3D imaging of mouse and human intrahepatic bile ducts in homeostasis and liver injurySemantic proximity Read

Glisson’s capsule structure and function is altered in cirrhotic patients irrespective of etiologySemantic proximity Read

Depth-Variant Deconvolution Applied to Widefield Microscopy for Rapid Large-Volume Tissue ImagingSemantic proximity Read