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Development and validation of direct RT-LAMP for SARS-CoV-2

2020-05-04

Abstract excerpt

We have developed a reverse-transcriptase loop mediated amplification (RT-LAMP) method targeting genes encoding the Spike (S) protein and RNA-dependent RNA polymerase (RdRP) of SARS-CoV-2. The LAMP assay achieves comparable limit of detection as commonly used RT-PCR protocols based on artificial targets, recombinant Sindbis virus, and clinical samples. Clinical validation of single-target (S gene) LAMP (N=120) sho...

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Identifiers and source

Literature Corpus work
072f64d7-f8d5-5d49-827b-a6076472a449
DOI
10.1101/2020.04.29.20075747
Open publication

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Development and validation of direct RT-LAMP for SARS-CoV-2DOI 10.1101/2020.04.29.20075747
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