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A Lymph Node Targeted Adjuvant and Engineered Subunit Vaccine Promotes Potent Immunity to Epstein-Barr Virus in HLA-expressing Mice

2022-07-13

Abstract excerpt

<title>Abstract</title> <p>Recent emergence of a causal like between Epstein-Barr virus (EBV) and multiple sclerosis has generated considerable interest in the development of an effective vaccine against EBV. Here we describe a novel vaccine formulation based on a lymph node targeting Amphiphile (AMP) vaccine adjuvant, AMP-CpG, admixed with EBV gp350 glycoprotein and a novel EBV-polyepitope protein (EBVpoly) that...

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Literature Corpus work
066d24c1-e627-5cf6-8526-4257b6931e84
DOI
10.21203/rs.3.rs-1763329/v1
Open publication

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A Lymph Node Targeted Adjuvant and Engineered Subunit Vaccine Promotes Potent Immunity to Epstein-Barr Virus in HLA-expressing MiceDOI 10.21203/rs.3.rs-1763329/v1
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