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Replicability of multivariate brain-behaviour associations depends on clinical profile

2025-10-09

Abstract excerpt

Recent work suggests that thousands of individuals are required in multivariate brain-behaviour analyses to obtain consistently replicable results. Some believe, however, that smaller sample sizes may be sufficient if specific subpopulations are targeted. We investigate how sample size and cohort composition influence the replicability of Canonical Correlation Analysis (CCA) results using the UK Biobank (N=40,514)...

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Literature Corpus work
064e8ad3-1582-5998-98eb-5062c7b8c7ce
DOI
10.1101/2025.10.08.674881
Open publication

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Replicability of multivariate brain-behaviour associations depends on clinical profileDOI 10.1101/2025.10.08.674881
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