Article
On the replicability of diffusion weighted MRI-based brain-behavior models.
Communications biology - 30 Oct 2025
Kotikalapudi Raviteja, Kincses Balint, Gallitto Giuseppe, Englert Robert, Hoffschlag Kevin, Li Jialin, Büchel Christian, Bingel Ulrike, Spisak Tamas
Abstract excerpt
Replicability of anatomical and functional MRI-based inter-individual BWAS has been extensively discussed recently. This study reports a comprehensive evaluation of BWAS replicability based on structural connectomes (streamlines, FA, MD, RD, AD). Overall, 36%(21/58) of brain-phenotype associations were replicable in the HCP dataset with atleast one of the DWI metrics, and a discovery sample size n ≤ 425 (total...
Read the complete abstract on PubMedTopics
- Humans
- Brain
- Diffusion Magnetic Resonance Imaging
- Male
- Connectome
- Female
