Article

Meta-topologies define distinct anatomical classes of brain tumors linked to histology and survival

2021-11-21

Abstract excerpt

<h4>Background</h4> The current WHO classification integrates histological and molecular features of brain tumors. The aim of this study was to identify generalizable topological patterns with the potential to add an anatomical dimension to the classification of brain tumors. <h4>Methods</h4> We applied non-negative matrix factorization as an unsupervised pattern discovery strategy to the fine-grained topographic...

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Literature Corpus work: 061040f3-2e6f-5925-a67b-fac9fad68808
DOI: 10.1101/2021.11.20.21266624

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