Article

Sparse, trainable subnetworks for multi-omics integration: a cross-validated evaluation of the Lottery Ticket Hypothesis across nutrigenomic, toxicogenomic, and oncogenomic datasets

2026-05-26

Abstract excerpt

Multi-omics integration, the joint analysis of two or more high-dimensional molecular data types collected on the same biological samples, is now a standard analytical approach across nutrigenomics, toxicogenomics, microbiome research, and disease genomics. Existing methods sit on a trade-off between expressiveness and interpretability: latent-variable methods such as MOFA and DIABLO yield compact, biologically in...

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Literature Corpus work: 05f7247b-7d18-5a7c-84da-62d2e096742a
DOI: 10.64898/2026.05.22.727123

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