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Naturally occurring cobalamin (B <sub>12</sub> ) analogs can function as cofactors for human methylmalonyl-CoA mutase

2020-03-23

Abstract excerpt

Cobalamin, commonly known as vitamin B 12 , is an essential micronutrient for humans because of its role as an enzyme cofactor. Cobalamin is one of over a dozen structurally related compounds – cobamides – that are found in food and are produced by microorganisms in the human gut. Very little is known about how different cobamides affect B 12 -dependent metabolism in human cells. Here, we test in vitro how dive...

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Identifiers and source

Literature Corpus work
05d0d85a-a316-5d48-b301-eaa6b15c2133
DOI
10.1101/2020.03.20.997551
Open publication

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Naturally occurring cobalamin (B <sub>12</sub> ) analogs can function as cofactors for human methylmalonyl-CoA mutaseDOI 10.1101/2020.03.20.997551
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