Article

Optimal Drug Dosing to Prevent Chemotherapy Induced Neutropenia

2023-01-25

Abstract excerpt

In the first part of this paper, we have considered the well-known myelosuppression mathematical model of Lena Friberg and her coworkers from the system analysis point of view. We have studied the linearized model at steady state and considered its stability, controllability, observability, and scaling of model variables. It was noticed that the linearized dynamics of two state variables is slow (corresponding to...

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Literature Corpus work: 05a3cfe0-bf5e-52dd-9e48-aa9f731c14f8
DOI: 10.21203/rs.3.rs-2504603/v1

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