Article
Machine learning-based analysis reveals potential diagnostic gene biomarkers associated with immune infiltration in patients with osteoarthritis
2025-12-02
Abstract excerpt
<title>Abstract</title> <p>Objective We aimed to find and validate reliable diagnostic markers in osteoarthritis (OA) and to explore the links with immunophenotypes. Materials and Methods For this study, we screened the Gene Expression Omnibus (GEO) dataset of three OA synovial samples for genes that differed between the disease and normal groups. Subsequently, multiple machine learning algorithms as well as scre...
Topics
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- Cancer-related molecular mechanisms research
- Cytokine Signaling Pathways and Interactions
- Ferroptosis and cancer prognosis
- Immune cells in cancer
- Inflammatory mediators and NSAID effects
- Osteoarthritis Treatment and Mechanisms
- Rheumatoid Arthritis Research and Therapies
- Single-cell and spatial transcriptomics
Identifiers and source
- Literature Corpus work
- 049f164f-a389-5676-a9e1-4ec991ca7566
- DOI
- 10.21203/rs.3.rs-7616797/v1
