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Article

Shotgun metagenomic sequencing analysis as a diagnostic strategy for patients with lower respiratory tract infections

2025-04-25

Abstract excerpt

<h4>Introduction</h4> Diagnosing lower respiratory infections (LRIs) using conventional diagnostic methods (CDMs) presents limitations in detecting suspected pathogens. This study compares the latest CDMs with shotgun metagenomic sequencing (SMS) for bronchoalveolar lavage (BAL) fluid. The primary objective is to enhance pathogen detection using SMS. <h4>Materials and Methods</h4> A total of 16 BAL fluid samples f...

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Literature Corpus work
04940aee-0f21-5373-ab99-576993d4c702
DOI
10.1101/2025.04.24.25326335
Open publication

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Shotgun metagenomic sequencing analysis as a diagnostic strategy for patients with lower respiratory tract infectionsDOI 10.1101/2025.04.24.25326335
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