Article

ALTERATION OF SPLICING PATTERN ON ANGIOTENSIN CONVERTING ENZYME GENE DUE TO THE INSERTION OF ALU ELEMENTS

2015-05-07

Abstract excerpt

Angiotensin Converting Enzyme ( ACE ) is a zinc metallopeptidase that has a significant role in blood pressure regulation and the pathophysiology of hypertension. ACE has two protein domains, the N-domain and the C-domain, which each has a single active site that functions independently of each other. There is insertion/deletion by 288 bp Alu elements in the intron 16 of ACE gene. The Alu elements potentially alte...

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Literature Corpus work: 044dd3ca-a426-5475-81e3-79380b536916
DOI: 10.34040/ijcb.4.2.2015.61

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