Article

Development of an in vitro method to assess the immunogenicity of biologics in the prevention of infectious diseases

2024-08-07

Abstract excerpt

<title>Abstract</title> <p>We present a series of preclinical studies focusing on developing <italic>in vitro</italic> 2D and 3D models for assessing the immunogenic factors in preventing infectious diseases. Human peripheral blood mononuclear cells (PBMC) and Calu-3 cell lines (bronchial epithelial cells) were used to develop 2D and 3D models. Peptides: Spike-S1-His, nucleocapsid-His and adjuvants: human adenovi...

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Literature Corpus work: 03cb2435-bc61-5f37-b7c8-3d113a2e55b6
DOI: 10.21203/rs.3.rs-4699723/v1

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