Article

The role of B cells in the pathogenesis of chronic graft-versus-host disease

2014-01-01

Abstract excerpt

Chronic graft-versus-host disease (cGVHD) remains a major complication of allogeneic haematopoietic stem cell transplantation. Traditionally, GVHD has been approached as a T-cell-mediated process and current therapies reflect this understanding. The successful treatment of a proportion of refractory cGVHD patients with a CD20-depleting-agent supports a pathological role for B cells. To study the role of B cells in...

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Literature Corpus work: 039e5874-04d9-584d-8b91-bd6423a4e9f9
DOI: 10.25560/29854

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