Article

Predicting functionally important breast cancer SNPs using pleiotropy, conservation, and protein structure

2024-01-02

Abstract excerpt

<h4>Motivation</h4> With over 24,000 SNPs associated with breast cancer in ClinVar, there is a need to prioritize the subset most likely to be causally linked to diagnostic, prognostic, and other clinical outcomes of disease. Building off currently known breast cancer oncogenes and SNPs, we identify the subset of SNPs with pleiotropic effects, with the goal of identifying mutations functionally relevant to diseas...

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Literature Corpus work: 03978416-f0a3-5f9b-8e41-b8fd21b894bb
DOI: 10.1101/2024.01.01.573831

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