Back to search

Article

Integrative Transcriptomic and Machine Learning Approaches to decipher Mitochondrial Gene Regulation in severe <i>Plasmodium vivax</i> Malaria

2025-07-02

Abstract excerpt

Mitochondria in Plasmodium vivax are functionally vital despite possessing a highly reduced genome and differing substantially from the human organelle. Beyond their classical role in energy production, they dynamically coordinate processes like pyrimidine biosynthesis and heme metabolism, adapting their functions across the intra-erythrocytic development cycle (IDC). Their unique architecture and stage-specific...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
03725776-8023-5559-882c-7a0bdaea6f0e
DOI
10.1101/2025.07.01.662590
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Integrative Transcriptomic and Machine Learning Approaches to decipher Mitochondrial Gene Regulation in severe <i>Plasmodium vivax</i> MalariaDOI 10.1101/2025.07.01.662590
Differential expression of mitochondria-associated genes in clinical samples of <i>Plasmodium falciparum</i> showing severe manifestationsSemantic proximity
Malian children infected with <i>Plasmodium ovale</i> and <i>Plasmodium falciparum</i> display very similar gene expression profilesSemantic proximity
New insights into the blood‐stage transcriptome of <i>Plasmodium falciparum</i> using RNA‐SeqSemantic proximity
Analysis of <i>Plasmodium vivax</i> schizont transcriptomes from field isolates reveals heterogeneity of expression of genes involved in host-parasite interactionsSemantic proximity
<i>In vivo</i> gene expression analyses provide unique insights on <i>P. vivax</i> gametocytogenesis and chloroquine responseSemantic proximity
Transcriptomic analyses of differentially expressed genes, micro RNAs and long-non-coding RNAs in severe, symptomatic and asymptomatic malaria infectionSemantic proximity
Plasmodium vivax transcriptomics: What is new?Semantic proximity
The transcriptome of <i>Plasmodium vivax</i> reveals divergence and diversity of transcriptional regulation in malaria parasitesSemantic proximity
Single-cell RNA profiling of <i>Plasmodium vivax</i> -infected hepatocytes reveals parasite- and host- specific transcriptomic signatures and therapeutic targetsSemantic proximity
Single-cell transcriptomics to define <i>Plasmodium falciparum</i> stage-transition in the mosquito midgutSemantic proximity
A single-cell atlas of <i>Plasmodium falciparum</i> transmission through the mosquitoSemantic proximity
A Tale of Two Parasites: A Glimpse into the RNA Methylome of Patient-derived <i>Plasmodium falciparum</i> and <i>Plasmodium vivax</i> isolatesSemantic proximity
Select a neighboring publication to make it the new centre.