Article

Analysis of complex chromosomal rearrangements using a combination of current molecular cytogenetic techniques

2022-03-02

Abstract excerpt

<h4>Background: </h4> Using combined fluorescence in situ hybridization (FISH) and high-throughput whole genome sequencing (WGS) molecular cytogenetic technology, we aim to analyze the junction breakpoints of complex chromosome rearrangements (CCR) that were difficult to identify by conventional karyotyping analysis and further characterize the genetic causes of recurrent spontaneous abortion. Results By leveragi...

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Literature Corpus work: 0355855d-0b1e-59b1-97ac-46af682e645c
DOI: 10.21203/rs.3.rs-1402523/v1

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