Chemical Coverage of the Human Reactome

Abstract excerpt

Chemical probes and chemogenomic compounds are valuable tools to link gene to phenotype, explore human biology and uncover novel targets for precision medicine. A growing federation of scientists is contributing to the mission of Target 2035 – discovering chemical tools for all druggable human proteins by the year 2035. It is expected that these compounds will enable the understanding of the regulation of cellular...

Topics

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• Chemistry
• Disease
• Drug Therapy
• Health
• Monoclonal and Polyclonal Antibodies Research
• Phenotype
• Protein Degradation and Inhibitors
• Ubiquitin and proteasome pathways

Identifiers and source

Literature Corpus work

033f9226-d0c4-54d1-aca3-8d42f38b2fd8

DOI

10.1101/2024.04.23.590739