Article

Alterations to DNA methylation patterns induced by chemotherapy treatment are associated with negative impacts on the olfactory pathway

2023-06-09

Abstract excerpt

<h4>Background: </h4> Exposure to cytotoxic chemotherapy treatment may alter DNA methylation (DNAm) in breast cancer patients. Methods We performed DNAm analysis in 125 breast cancer patients with blood drawn before and after chemotherapy, using the Illumina MethylationEPIC array. DNAm changes of 588,798 individual CpGs and 41,222 promoters were evaluated using linear regression models adjusted for monocyte propo...

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Literature Corpus work: 0300a8bc-bc93-5e78-ab33-11f66d85836c
DOI: 10.21203/rs.3.rs-3022133/v1

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