Article

Rising Disease Prevalence Signals Epigenetic Degeneration in Humans

2025-11-27

Abstract excerpt

Two clear epidemiological patterns are emerging in human populations: first, a rise in the prevalence of numerous diseases and phenotypic conditions; and second, the increasing appearance of conditions once associated with old age in younger individuals. This study explores these patterns using the Accumulated Mean Annual Variation (AMAV), a novel metric designed to integrate heterogeneous trend data from multiple...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 02944174-2e19-5c44-94d2-904192b05f1c
DOI: 10.20944/preprints202508.2157.v2

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Rising Disease Prevalence Signals Epigenetic Degeneration in HumansDOI 10.20944/preprints202508.2157.v2Read

Rising Disease Prevalence Signals Epigenetic Degeneration in HumansSemantic proximity Read

Current perspectives on the cellular and molecular features of epigenetic ageingSemantic proximity Read

Epigenetic Clocks: In Aging-Related and Complex DiseasesSemantic proximity Read

The Architecture of Aging: How Ageing Drives Disease (Blueprint Theory)Semantic proximity Read

Evolutionary genetics of ageing.Semantic proximity Read

Sex differences in biological aging with a focus on human studiesSemantic proximity Read

Patterns of Aging Biomarkers, Mortality, and Damaging Mutations Illuminate the Beginning of Aging and Causes of Early-Life Mortality.Semantic proximity Read

Evolutionary genetic bases of longevity and senescence.Semantic proximity Read

Gender, aging and longevity in humans: an update of an intriguing/neglected scenario paving the way to a gender-specific medicineSemantic proximity Read

Epigenetic Clock: DNA Methylation as a Marker of Biological Age and Age-Associated DiseasesSemantic proximity Read

Wandering along the epigenetic timelineSemantic proximity Read

Epigenetic measures of ageing predict the prevalence and incidence of leading causes of death and disease burdenSemantic proximity Read