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BPP43_05035 is a <i>Brachyspira pilosicoli</i> cell surface adhesin that weakens the integrity of the epithelial barrier during infection

2024-04-06

Abstract excerpt

The anaerobic spirochete Brachyspira causes intestinal spirochetosis, characterized by the intimate attachment of bacterial cells to the colonic mucosa, potentially leading to symptoms such as diarrhea, abdominal pain, and weight loss. Despite the clinical significance of Brachyspira infections, the mechanism behind the interaction between Brachyspira and the colonic epithelium is not known. In this study, we c...

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Literature Corpus work
022420ea-8b45-5c64-9f9e-c3cf8171c68b
DOI
10.1101/2024.04.06.584567
Open publication

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