Article

Machine Learning-Enabled EEG Biomarkers Predict Divergent Antidepressant and Placebo Response in a Clinical Trial of Major Depression

2025-05-29

Abstract excerpt

<h4>Background</h4> Major depressive disorder (MDD) is a heterogeneous neuropsychiatric disorder with highly variable antidepressant outcomes. In randomized controlled trials (RCTs), low drug-placebo differences and high placebo response rates are persistent challenges. An objective biomarker that can prospectively identify which patients will respond to antidepressant or placebo could greatly enhance both clinica...

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Literature Corpus work: 0203f31e-7b08-5c2a-8d28-27c523b45c2b
DOI: 10.1101/2025.05.29.25328167

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Machine Learning-Enabled EEG Biomarkers Predict Divergent Antidepressant and Placebo Response in a Clinical Trial of Major DepressionDOI 10.1101/2025.05.29.25328167Read

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