Article

Sex differences and risk factors for bleeding in Alagille syndrome

2021-04-14

Abstract excerpt

Spontaneous lethal bleeds are major cause of death in the pediatric liver disease Alagille syndrome (ALGS), yet risk factors and screening methods have not been established. We performed a systematic review and identified significantly more female than male patients with idiopathic intracranial hemorrhage (10:1). We investigated bleeding and vasculature in patients and a mouse model for ALGS ( Jag1 Ndr/Ndr mice)...

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Literature Corpus work: 01ca9ff7-5ccc-5874-b654-375807e8f3b6
DOI: 10.1101/2021.04.13.439679

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