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Prolonged ischemia induces oxidative stress, affects extra cellular matrix gene expression and compromises the viability of cancellous bone grafts

2025-12-22

Abstract excerpt

<title>Abstract</title> <p> Background Despite growing insights into the pathophysiology of non-union formation, failed fracture healing remains a major complication in trauma and orthopedic surgery. The transplantation of cancellous bone grafts represents the gold standard for the treatment of atrophic non-unions and large-scaled bone defects. Depending on the type of procedure and the available personnel, the...

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Literature Corpus work
01b1684c-3b5a-52e8-a925-4f171be47115
DOI
10.21203/rs.3.rs-8186169/v1
Open publication

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Prolonged ischemia induces oxidative stress, affects extra cellular matrix gene expression and compromises the viability of cancellous bone graftsDOI 10.21203/rs.3.rs-8186169/v1
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