Back to search

Article

Adverse events reported during weekly isoniazid-rifapentine (3HP) tuberculosis preventive treatment among people living with HIV in Uganda

2024-08-09

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background</h4> Short-course tuberculosis (TB) prevention regimens, including 12 weeks of isoniazid and rifapentine (3HP), are increasingly used in high TB-burden countries. Despite established safety and tolerability in efficacy trials, 3HP-related adverse events (AE) could differ in routine settings. Real-world data on AE type, frequency, and timing is crucial for health systems considering...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
01422bd8-8809-5aaa-9380-2ffb334e3bbf
DOI
10.1101/2024.08.08.24311632
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Adverse events reported during weekly isoniazid-rifapentine (3HP) tuberculosis preventive treatment among people living with HIV in UgandaDOI 10.1101/2024.08.08.24311632
Outcomes of the three-month weekly isoniazid with rifapentine (3HP) versus the six-month isoniazid preventive therapy (6H) among people newly enrolled in HIV care in western KenyaSemantic proximity
High initiation but sub-optimal completion of tuberculosis preventive treatment among people living with HIV on ART, persistent tuberculosis incidence and programmatic implications: Findings from a two-year multi-country cohort studySemantic proximity
Assessment of Pharmacotherapy and Clinical Outcomes of Treatment for the Development of Cardiovascular Disease among Tuberculosis PatientsSemantic proximity
Treatment outcomes of drug-resistant <i>Mycobacterium tuberculosis</i> infection in Cameroon: a systematic review and meta-analysisSemantic proximity
Three months of weekly rifapentine and isoniazid versus four months of rifampicin for tuberculosis infection: a randomised controlled trialSemantic proximity
Protocol for a phase 2, partially-blinded, randomised trial assessing the safety and efficacy of sorfequiline or bedaquiline, in combination with pretomanid and linezolid in adult participants with newly diagnosed, drug-sensitive, smear-positive pulmonary tuberculosis (NC-009)Semantic proximity
Isoniazid Concentration and NAT2 Genotype Predict Risk of Systemic Drug Reactions during 3HP for LTBISemantic proximity
Incidence and associated risk factors of antituberculosis drug induced hepatotoxicity among TB patientsSemantic proximity
Digital adherence technologies to improve tuberculosis treatment outcomes: a cluster-randomised superiority trialSemantic proximity
Empiric tuberculosis treatment and 12-month mortality among sputum GeneXpert-negative adults living with HIV in Uganda in the era of widespread Antiretroviral therapy: A prospective cohort studySemantic proximity
Adverse Drug Reactions to Anti-TB Drugs: Pharmacogenomics Perspective for Identification of Host Genetic Markers.Semantic proximity
Association of Drug Metabolic Enzyme Genetic Polymorphisms and Adverse Drug Reactions in Patients Receiving Rifapentine and Isoniazid Therapy for Latent Tuberculosis.Semantic proximity
Select a neighboring publication to make it the new centre.