Article

Unsupervised idealization of ion channel recordings by Minimum Description Length: Application to human PIEZO1-channels

2017-02-06

Abstract excerpt

Researchers can investigate the mechanistic and molecular basis of many physiological phenomena in cells by analyzing the fundamental properties of single ion channels. These analyses entail recording single channel currents and measuring current amplitudes and transition rates between conductance states. Since most electrophysiological recordings contain noise, the data analysis can proceed by idealizing the reco...

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Literature Corpus work: 013bc64d-b15e-5058-8ea0-d56ffb3699d0
DOI: 10.1101/106187

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