Article

A multimodal iPSC platform for cystic fibrosis drug testing

2021-06-23

Abstract excerpt

Cystic fibrosis (CF) is a monogenic lung disease caused by dysfunction of the cystic fibrosis transmembrane regulator (CFTR) anion channel, resulting in significant morbidity and mortality. The progress in elucidating the role of the CFTR channel using established animal and cell-based models led to the recent discovery of effective CFTR modulators for most individuals with CF. However, a subset of individuals wit...

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Literature Corpus work: 0098b9b0-78eb-5fb6-b41a-90ae4db505f1
DOI: 10.1101/2021.06.21.448578

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