Article

Functional studies of deafness-associated pendrin and prestin variants

2024-01-26

Abstract excerpt

<h4>ABSTRACT</h4> Pendrin and prestin are evolutionary conserved membrane proteins that are essential for normal hearing. Pendrin is an anion transporter required for normal development and maintenance of ion homeostasis in the inner ear, while prestin is a voltage-dependent motor responsible for cochlear amplification essential for high sensitivity and frequency selectivity of mammalian hearing. Dysfunction of t...

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Literature Corpus work: 005ec4ce-d141-55aa-a8c5-54741816877e
DOI: 10.1101/2024.01.23.576877

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