Article
Targeted disruption of gene function in Drosophila by RNA interference (RNA-i): a role for nautilus in embryonic somatic muscle formation.
Proceedings of the National Academy of Sciences of the United States of America - 16 Feb 1999
Misquitta L, Paterson B M
Abstract excerpt
The expression of the MyoD gene homolog, nautilus (nau), in the Drosophila embryo defines a subset of mesodermal cells known as the muscle "pioneer" or "founder" cells. These cells are thought to establish the future muscle pattern in each hemisegment. Founders appear to recruit fusion-competent mesodermal cells to establish a particular muscle fiber type. In support of this concept every somatic muscle in the...
Topics
- Animals
- Chorion
- Drosophila
- Drosophila Proteins
- Embryo, Nonmammalian
- Embryonic Induction
- Female
- Gene Expression Regulation, Developmental
- Insect Proteins
- Larva
- Muscle Proteins
- Muscles
- Mutagenesis
- Phenotype
- RNA, Antisense
- RNA, Double-Stranded
- Transcription Factors