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Article

A role for the Drosophila neurogenic genes in mesoderm differentiation.

Cell - 18 Oct 1991

Corbin V, Michelson A M, Abmayr S M, Neel V, Alcamo E, Maniatis T, Young M W

Abstract excerpt

The neurogenic genes of Drosophila have long been known to regulate cell fate decisions in the developing ectoderm. In this paper we show that these genes also control mesoderm development. Embryonic cells that express the muscle-specific gene nautilus are overproduced in each of seven neurogenic mutants (Notch, Delta, Enhancer of split, big brain, mastermind, neuralized, and almondex), at the apparent expense of...

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Source

Identifiers

PMID: 1913825
DOI: 10.1016/0092-8674(91)90183-y

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Research trail→

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A role for the Drosophila neurogenic genes in mesoderm differentiation.PMID 1913825Read ↗

The function of the neurogenic genes during epithelial development in the Drosophila embryo.Semantic proximity Read ↗

A role for nautilus in the differentiation of muscle precursors.Semantic proximity Read ↗

Expression of a MyoD family member prefigures muscle pattern in Drosophila embryos.Semantic proximity Read ↗

Evidence for a novel Notch pathway required for muscle precursor selection in Drosophila.Semantic proximity Read ↗

Loss-of-function mutations reveal that the Drosophila nautilus gene is not essential for embryonic myogenesis or viability.Semantic proximity Read ↗

Wingless signaling induces nautilus expression in the ventral mesoderm of the Drosophila embryo.Semantic proximity Read ↗

Stereotypic founder cell patterning and embryonic muscle formation in Drosophila require nautilus (MyoD) gene function.Semantic proximity Read ↗

Targeted disruption of gene function in Drosophila by RNA interference (RNA-i): a role for nautilus in embryonic somatic muscle formation.Semantic proximity Read ↗

Genetic control of dorsoventral patterning and neuroblast specification in the Drosophila Central Nervous System.Semantic proximity Read ↗

The mutant not enough muscles (nem) reveals reduction of the Drosophila embryonic muscle pattern.Semantic proximity Read ↗

Antineurogenic phenotypes induced by truncated Notch proteins indicate a role in signal transduction and may point to a novel function for Notch in nuclei.Semantic proximity Read ↗

Mastermind mutations generate a unique constellation of midline cells within the Drosophila CNS.Semantic proximity Read ↗

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