Article
Tuberculosis and chronic hepatitis B virus infection in Africans and variation in the vitamin D receptor gene.
The Journal of infectious diseases - 1 Mar 1999
Bellamy R, Ruwende C, Corrah T, McAdam K P, Thursz M, Whittle H C, Hill A V
Abstract excerpt
The active metabolite of vitamin D, 1,25 dihydroxyvitamin D3, is an important immunoregulatory hormone [1]. Its effects are exerted by interaction with the vitamin D receptor, which is present on human monocytes and activated T and B lymphocytes. Variation in the vitamin D receptor gene was typed in 2015 subjects from large case-control studies of three major infectious diseases: tuberculosis, malaria, and...
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