Article
Genetic linkage of exotoxin alleles and emm gene markers for tissue tropism in group A streptococci.
The Journal of infectious diseases - 1 Mar 1999
Bessen D E, Izzo M W, Fiorentino T R, Caringal R M, Hollingshead S K, Beall B
Abstract excerpt
In group A streptococci, genetic markers for principal tissue reservoir are located within emm genes, which encode surface proteins that have a role in virulence. A worldwide collection of 160 isolates was evaluated for two traits: chromosomal emm gene markers for tissue tropism (designated patterns A-E), and bacteriophage-associated genes (speA and speC) encoding pyrogenic exotoxins. The speA and speC alleles of...
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