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Article

Toxin-gene profile heterogeneity among endemic invasive European group A streptococcal isolates.

The Journal of infectious diseases - 15 Nov 2003

Schmitz Franz-Josef, Beyer Andreas, Charpentier Emmanuelle, Normark Birgitta Henriques, Schade Marc, Fluit Ad C, Hafner Dieter, Novak Rodger

Abstract excerpt

We determined the toxin-gene profiles of 239 endemic, invasive group A streptococcal (GAS) isolates that circulated, within a 5-year period, in European university hospitals. Profiling was performed by use of multiplex polymerase chain reaction that screened for 9 streptococcal pyrogenic exotoxins (speA, speB, speC, speF, speG, speH, speJ, ssa, and smeZ). Analysis revealed that invasive GAS isolates do not share...

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Identifiers

PMID: 14624385
DOI: 10.1086/379230

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