Article
Genetic diversity and exotoxin A production of group A streptococci causing sepsis.
Journal of Korean medical science - 1 Apr 2006
Koh Eun Ha, Lee Nam Yong, Kim Eui Chong, Kim Sunjoo
Abstract excerpt
The M protein and streptococcus pyrogenic exotoxin (SPE A) are important virulence factors in group A streptococci (GAS) infections. The emm types of GAS strains isolated from patients with sepsis were determined by sequencing the 5' N-terminus of the emm gene, encoding the M protein, and clonality analysis using pulsed-field gel electrophoresis. The presence of speA and production of SPE A were also examined....
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