Genetic diversity and exotoxin A production of group A streptococci causing sepsis.

doi:10.3346/jkms.2006.21.2.193

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Article

Genetic diversity and exotoxin A production of group A streptococci causing sepsis.

Journal of Korean medical science - 1 Apr 2006

Koh Eun Ha, Lee Nam Yong, Kim Eui Chong, Kim Sunjoo

Abstract excerpt

The M protein and streptococcus pyrogenic exotoxin (SPE A) are important virulence factors in group A streptococci (GAS) infections. The emm types of GAS strains isolated from patients with sepsis were determined by sequencing the 5' N-terminus of the emm gene, encoding the M protein, and clonality analysis using pulsed-field gel electrophoresis. The presence of speA and production of SPE A were also examined....

Topics

Adolescent
Adult
Aged
Bacterial Proteins
Child
Child, Preschool
DNA, Bacterial
Exotoxins
Female
Genetic Variation
Genotype
Humans
Infant
Male
Membrane Proteins
Middle Aged
Sepsis
Streptococcal Infections

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Identifiers

PMID: 16614500
DOI: 10.3346/jkms.2006.21.2.193
PMCID: PMC2733990

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