Article
Cadherin function in junctional complex rearrangement and posttranslational control of cadherin expression.
The American journal of physiology - 1 Feb 1999
Troxell M L, Chen Y T, Cobb N, Nelson W J, Marrs J A
Abstract excerpt
The role of E-cadherin, a calcium-dependent adhesion protein, in organizing and maintaining epithelial junctions was examined in detail by expressing a fusion protein (GP2-Cad1) composed of the extracellular domain of a nonadherent glycoprotein (GP2) and the transmembrane and cytoplasmic domains of E-cadherin. All studies shown were also replicated using an analogous cell line that expresses a mutant cadherin...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
