Article
New DNA polymorphisms of human MMH/OGG1 gene: prevalence of one polymorphism among lung-adenocarcinoma patients in Japanese.
International journal of cancer - 5 Jan 1999
Ishida T, Takashima R, Fukayama M, Hamada C, Hippo Y, Fujii T, Moriyama S, Matsuba C, Nakahori Y, Morita H, Yazaki Y, Kodama T, Nishimura S, Aburatani H
Abstract excerpt
MMH/OGG1 is an 8-hydroxyguanine-specific DNA glycosylase/AP-lyase, one of the mutator enzymes for the excision repair of 8-hydroxyguanine. DNA polymorphisms in human MMH/OGG1 gene were newly identified and analyzed to examine a possible association with lung-cancer risk by a population-based stud...
Topics
- Adenocarcinoma
- Base Sequence
- Carcinoma, Non-Small-Cell Lung
- Carcinoma, Squamous Cell
- DNA-Formamidopyrimidine Glycosylase
- Exons
- Female
- Genetic Predisposition to Disease
- Humans
- Japan
- Lung Neoplasms
- Male
- N-Glycosyl Hydrolases
- Odds Ratio
