Discordant organ laterality in monozygotic twins with primary ciliary dyskinesia

Abstract excerpt

Primary ciliary dyskinesia (PCD) is a genetic disease characterized by abnormal ciliary structure and function, impaired mucociliary clearance, and chronic middle ear, sinus, and lung disease. PCD is associated with situs inversus in approximately 50% of the patients. One proposed explanation for this relationship is that normal ciliary function plays a role in normal organ orientation, whereas organ orientation...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Cleft Lip and Palate Research
• Share to Craniofacial Disorders and Treatments
• Share to Cystic Fibrosis Research Advances