Article
Characterization and nucleotide sequence of CARB-6, a new carbenicillin-hydrolyzing beta-lactamase from Vibrio cholerae.
Antimicrobial agents and chemotherapy - 1 Feb 1999
Choury D, Aubert G, Szajnert M F, Azibi K, Delpech M, Paul G
Abstract excerpt
A clinical strain of Vibrio cholerae non-O1 non-O139 isolated in France produced a new beta-lactamase with a pI of 5.35. The purified enzyme, with a molecular mass of 33,000 Da, was characterized. Its kinetic constants show it to be a carbenicillin-hydrolyzing enzyme comparable to the five previo...
Topics
- Amino Acid Sequence
- Base Sequence
- Carbenicillin
- Molecular Sequence Data
- Molecular Weight
- Mutation
- Penicillins
- Sequence Homology, Amino Acid
- Substrate Specificity
- Vibrio cholerae
- beta-Lactamases