Genetic diversity, biochemical properties, epidemiology, and detection methods of IMP- and VIM-type carbapenemases.

Abstract excerpt

SUMMARYMetallo-beta-lactamases are an ever-growing problem. Since the discovery of the beta-lactamase of Bacillus cereus in the late 1960s, many class B beta-lactamases have been reported, with three main families being NDM-, IMP-, and VIM-like. IMP- and VIM-like carbapenemases have been identified in a wide variety of Gram-negative bacteria. VIM-type carbapenemases are widely distributed, primarily represented...

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