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Article

Insulin resistance and the polycystic ovary syndrome revisited: an update on mechanisms and implications.

Endocrine reviews - 1 Dec 2012

Diamanti-Kandarakis Evanthia, Dunaif Andrea

Abstract excerpt

Polycystic ovary syndrome (PCOS) is now recognized as an important metabolic as well as reproductive disorder conferring substantially increased risk for type 2 diabetes. Affected women have marked insulin resistance, independent of obesity. This article summarizes the state of the science since we last reviewed the field in the Endocrine Reviews in 1997. There is general agreement that obese women with PCOS are...

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Identifiers

PMID: 23065822
DOI: 10.1210/er.2011-1034
PMCID: PMC5393155

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