Article
Disorders of the calcium-sensing receptor.
Biochimica et biophysica acta - 10 Dec 1998
Thakker R V
Abstract excerpt
The human calcium-sensing receptor (CaSR) is a 1078-amino-acid cell surface protein which is expressed in the parathyroids, thyroid cells and the kidney, and is a member of the family of G protein-coupled receptors. The CaSR allows regulation of parathyroid hormone (PTH) secretion and renal tubular calcium reabsorption in response to alterations in extracellular calcium concentrations. The human CaSR gene is...
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