Article
Diseases associated with the extracellular calcium-sensing receptor.
Cell calcium - 1 Mar 2004
Thakker R V
Abstract excerpt
The human calcium-sensing receptor (CaSR) is a 1078 amino acid cell surface protein, which is predominantly expressed in the parathyroids and kidney, and is a member of the family of G protein-coupled receptors. The CaSR allows regulation of parathyroid hormone (PTH) secretion and renal tubular calcium reabsorption in response to alterations in extracellular calcium concentrations. The human CaSR gene is located...
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