Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Disorders of the calcium-sensing receptor and partner proteins: insights into the molecular basis of calcium homeostasis.

Journal of molecular endocrinology - 1 Oct 2016

Hannan Fadil M, Babinsky Valerie N, Thakker Rajesh V

Abstract excerpt

The extracellular calcium (Ca(2+) o)-sensing receptor (CaSR) is a family C G protein-coupled receptor, which detects alterations in Ca(2+) o concentrations and modulates parathyroid hormone secretion and urinary calcium excretion. The central role of the CaSR in Ca(2+) o homeostasis has been highlighted by the identification of mutations affecting the CASR gene on chromosome 3q21.1. Loss-of-function CASR...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Calcium
Share to Carrier Proteins
Share to Disease Susceptibility

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to GTP-Binding Protein alpha Subunits

Share to Homeostasis

Share to Protein Transport

Share to Receptors, Calcium-Sensing

Share to Structure-Activity Relationship

Source

Open in PubMed Open full text

Identifiers

PMID: 27647839
DOI: 10.1530/JME-16-0124
PMCID: PMC5064759

Genes

CASR
GNA11

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Disorders of the calcium-sensing receptor and partner proteins: insights into the molecular basis of calcium homeostasis.PMID 27647839Read ↗

Rare diseases caused by abnormal calcium sensing and signalling.Semantic proximity Read ↗

Calcium-sensing receptor (CaSR) mutations and disorders of calcium, electrolyte and water metabolism.Semantic proximity Read ↗

Diseases associated with the extracellular calcium-sensing receptor.Semantic proximity Read ↗

[Disorders Caused by Mutations in Calcium-Sensing Receptor and Related Diseases.]Semantic proximity Read ↗

Calcimimetic and calcilytic therapies for inherited disorders of the calcium‐sensing receptor signalling pathwaySemantic proximity Read ↗

Molecular and clinical insights from studies of calcium-sensing receptor mutationsSemantic proximity Read ↗

Disorders of the calcium-sensing receptor.Semantic proximity Read ↗

Mutations of the calcium-sensing receptor (CASR) in familial hypocalciuric hypercalcemia, neonatal severe hyperparathyroidism, and autosomal dominant hypocalcemia.Semantic proximity Read ↗

Identification and characterization of a novel CASR mutation causing familial hypocalciuric hypercalcemia.Semantic proximity Read ↗

The calcium-sensing receptor and related diseases.Semantic proximity Read ↗

Calcium-sensing-related gene mutations in hypercalcaemic hypocalciuric patients as differential diagnosis from primary hyperparathyroidism: detection of two novel inactivating mutations in an Italian population.Semantic proximity Read ↗

Clinical and laboratory features of calcium-sensing receptor disorders: a systematic review.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.