Article
High density synthetic oligonucleotide arrays.
Nature genetics - 1 Jan 1999
Lipshutz R J, Fodor S P, Gingeras T R, Lockhart D J
Abstract excerpt
Experimental genomics involves taking advantage of sequence information to investigate and understand the workings of genes, cells and organisms. We have developed an approach in which sequence information is used directly to design high-density, two-dimensional rays of synthetic oligonucleotides. The GeneChipe probe arrays are made using spatially patterned, light-directed combinatorial chemical synthesis and...
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