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Article

Expression of endothelin 3 by mesenchymal cells of embryonic mouse caecum

1 Feb 1999

Abstract excerpt

BACKGROUND: Mutations in endothelin 3 (EDN3) and endothelin B receptor (EDNRB) genes cause terminal colonic aganglionosis in mice, and mutations in these genes have also been linked to the terminal aganglionosis seen in human Hirschsprung's disease. However, details of EDN3 expression during embryogenesis are lacking, and consequently the cellular mechanism by which EDN3 regulates innervation of the terminal gut...

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PMID: 9895385
DOI: 10.1136/gut.44.2.246

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Expression of endothelin 3 by mesenchymal cells of embryonic mouse caecumPMID 9895385Read ↗

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