Article
regA, a Volvox gene that plays a central role in germ-soma differentiation, encodes a novel regulatory protein.
Development (Cambridge, England) - 1 Feb 1999
Kirk M M, Stark K, Miller S M, Müller W, Taillon B E, Gruber H, Schmitt R, Kirk D L
Abstract excerpt
Volvox has two cell types: mortal somatic cells and immortal germ cells. Here we describe the transposon-tagging, cloning and characterization of regA, which plays a central role as a master regulatory gene in Volvox germ-soma differentiation by suppressing reproductive activities in somatic cell...
Topics
- Algal Proteins
- Amino Acid Sequence
- Cell Differentiation
- Chlorophyta
- Cloning, Molecular
- DNA Transposable Elements
- Gene Expression Regulation
- Molecular Sequence Data
- Mutation
- Nuclear Proteins
- Polymorphism, Restriction Fragment Length
- RNA, Messenger
- Repressor Proteins
- Sequence Analysis, DNA