Predicted anti-oestrogen resistance in BRCA-associated familial breast cancers.

doi:10.1016/s0959-8049(98)00248-2

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Article

Predicted anti-oestrogen resistance in BRCA-associated familial breast cancers.

European journal of cancer (Oxford, England : 1990) - 1 Oct 1998

Osin P, Gusterson B A, Philp E, Waller J, Bartek J, Peto J, Crook T

Abstract excerpt

There is controversy concerning the prognosis of breast cancers arising in women carrying loss of function mutations in the breast cancer susceptibility genes BRCA1 and BRCA2. This study was carried out to assess the likely hormone dependence of this group of tumours in comparison with an age and...

Topics

Adult
BRCA2 Protein
Breast Neoplasms
Carcinoma, Ductal, Breast
Cyclin D1
Female
Genes, BRCA1
Genetic Predisposition to Disease
Humans
Immunohistochemistry
Middle Aged
Neoplasm Proteins
Proteins
Receptors, Estrogen
Receptors, Progesterone
Transcription Factors
Trefoil Factor-1
Tumor Suppressor Proteins

Source

Open in PubMed

Identifiers

PMID: 9893652
DOI: 10.1016/s0959-8049(98)00248-2

Genes

BRCA1
BRCA2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9893652-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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