Article
Predicted anti-oestrogen resistance in BRCA-associated familial breast cancers.
European journal of cancer (Oxford, England : 1990) - 1 Oct 1998
Osin P, Gusterson B A, Philp E, Waller J, Bartek J, Peto J, Crook T
Abstract excerpt
There is controversy concerning the prognosis of breast cancers arising in women carrying loss of function mutations in the breast cancer susceptibility genes BRCA1 and BRCA2. This study was carried out to assess the likely hormone dependence of this group of tumours in comparison with an age and grade matched group of control sporadic tumours. We used quantitative immunohistochemical analysis for the oestrogen...
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