Article
IP6 in treatment of liver cancer. I. IP6 inhibits growth and reverses transformed phenotype in HepG2 human liver cancer cell line.
Anticancer research - 1 Jan 2000
Vucenik I, Tantivejkul K, Zhang Z S, Cole K E, Saied I, Shamsuddin A M
Abstract excerpt
Hepatocellular carcinoma (HCC) is a common tumor world-wide with extremely poor prognosis. Recent studies have shown that inositol hexaphosphate (IP6), a naturally occurring carbohydrate, has novel anti-cancer function in various in vitro and in vivo models. The aim of this study was to assess wh...
Topics
- Antineoplastic Agents
- Cell Differentiation
- Cell Division
- Cell Transformation, Neoplastic
- Cyclin-Dependent Kinase Inhibitor p21
- Cyclins
- Gene Expression Regulation, Neoplastic
- Genes, Tumor Suppressor
- Genes, p53
- Hepatoblastoma
- Humans
- Liver Neoplasms
- Phenotype
- Phytic Acid
- Tumor Cells, Cultured
- Tumor Suppressor Protein p53
- alpha-Fetoproteins