A chromosome 4p haplotype segregating with Parkinson's disease and postural tremor.

doi:10.1093/hmg/8.1.81

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Article

A chromosome 4p haplotype segregating with Parkinson's disease and postural tremor.

Human molecular genetics - 1 Jan 1999

Farrer M, Gwinn-Hardy K, Muenter M, DeVrieze F W, Crook R, Perez-Tur J, Lincoln S, Maraganore D, Adler C, Newman S, MacElwee K, McCarthy P, Miller C, Waters C, Hardy J

Abstract excerpt

We investigated a large family with levodopa-responsive, Lewy body parkinsonism in which the disease segregates as an apparent autosomal dominant trait. After performing a genome screen, we identified a chromosome 4p haplotype that segregates with the disease. However, this haplotype also occurs...

Topics

Chromosome Mapping
Chromosomes, Human, Pair 4
Female
Genes, Dominant
Haplotypes
Humans
Levodopa
Lod Score
Male
Parkinson Disease
Pedigree
Phenotype
Posture
Tremor

Source

Open in PubMed

Identifiers

PMID: 9887334
DOI: 10.1093/hmg/8.1.81

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9887334-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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