Article
Developmental loss of effect of a Chromosome 15 QTL on alcohol acceptance.
Mammalian genome : official journal of the International Mammalian Genome Society - 1 Dec 1998
McClearn G E, Tarantino L M, Hofer S M, Jones B, Plomin R
Abstract excerpt
Human alcohol abuse and alcoholism have clear developmental features, suggesting the possibility of changes over time in heritability and in quantitative genetic architecture, and raising prospects of identifying individual genes or quantitative trait loci (QTLs) that display different influence on alcohol-related phenotypes at different ages. The identification of specific loci showing such age-related changes...
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